The kidneys can also be damaged by misuse of some painkillers , prescription medicines and illegal drugs. Managing your condition. Genetics: Several forms of kidney disease have a genetic link and are caused by problems (mutations) in genes. Learn more. Diabetes Causes include diabetes and specific kidney diseases, which includes polycystic kidney disease. Nephrologist Daphne Knicely explains the causes and stages of chronic kidney disease. High blood pressure doesn’t just cause kidney disease, it can also occur as a result of kidney disease. Polycystic Kidney Disease, Alport Syndrome, Fabry Disease. Obesity Knowledge is power after all! These disorders can also involve and damage organs like the kidneys. Also known as chronic renal disease or nephropathy, chronic kidney disease (CKD) occurs when the kidneys cannot properly filter the fluids that pass through them. What do I mean by that? African Americans, Hispanics, Pacific Islanders, American Indians and Seniors are at increased risk. This means the kidneys don’t receive the oxygen and nutrients they need to work properly. Reflux nephropathy: Backflow of urine into the kidneys causes damage over time which can eventually lead to scarring of the kidneys and kidney disease. Kidney Coach. What Causes Chronic Kidney Diseases. Chronic kidney disease is long-term damage to the kidneys, the organs responsible for producing urine. High risk groups include those with diabetes, hypertension and family history of kidney failure. KidneyCoach.com is a website created to help people, like you, achieve kidney health and overall wellbeing through empowering and powerful content (articles, videos, and audio) each week. Careful control of blood sugar in diabetics helps to prevent such complications as kidney disease, coronary heart disease and stroke. Diabetes and high blood pressure are the most common causes of kidney disease. Patients need to note that both type 1 diabetes and type 2 diabetes can cause them to suffer from chronic kidney disease. Chronic kidney disease (CKD) (chronic renal disease) is a kidney disease where there is a gradual loss of kidney function. Heart disease is the major cause of death for all people with CKD. Take the Kidney Risk quiz to find out. Eg. Stones can also cause kidney infections which can lead to inflammation and scarring of the kidneys. Often it's the result of a combination of different problems. Each kidney contains about 1 million tiny filtering units, called nephrons. IgA nephropathy is classified as an autoimmune condition because the disease is due to the body’s immune system attacking the tissues in the kidney. If you continue to use this site we will assume that you are happy with it. Eg. Urinary tract- high blood sugar increases the likelihood of urinary tract infections which can later develop into infections of the kidneys. belong to a population group that has a high rate of diabetes or high blood pressure, such as African Americans, Hispanic Americans, Asian, Pacific Islanders, and American Indians. I’d love to see you there! There is no cure for chronic kidney disease, which means treatment is focussed on reducing symptoms. The main causes are high blood pressure and diabetes 4, 5. Chronic kidney disease (CKD) is a condition characterized by a gradual loss of kidney function over time. High blood pressure 3. Diabetes 2. CKD can be caused by: high blood pressure – over time, this can put strain on the small blood vessels in the kidneys and stop the kidneys working properly. https://www.heart.org/-/media/files/health-topics/high-blood-pressure/hbp-rainbow-chart-english-pdf-ucm_499220.pdf. Heart disease 4. The exact cause of IgA nephropathy is unknown in most cases, infections may contribute to it developing and its presence among certain families suggest there may be a genetic predisposition in some people. https://www.cdc.gov/kidneydisease/publications-resources/2019-national-facts.html?utm_source=miragenews&utm_medium=miragenews&utm_campaign=news. Worldwide, diabetes is the most common cause of CKD and the most frequent cause of end stage renal failure in most countries. Pharmaceutical drugs: Pharmaceutical drugs need to be broken down and detoxified which can place a burden on detoxifying organs such as the kidneys. I’m a firm believer that in order to heal yourself and treat any disease, you FIRST need to understand it. Early stages of CKD. As you may know, there are two types of kidney disease: Acute kidney injury (AKI), formerly called Acute renal failure (ARF) and Chronic Kidney Disease (CKD) which can lead to Chronic Kidney Failure (CRF). Also, kidney disease increases your risk of having heart and blood vessel disease. You may have an increased risk for kidney disease if you: GFR—glomerular filtration rate is the best test to measure your level of kidney function and determine your stage of kidney disease. Eg. The stages of kidney disease are based on how well the kidneys can do their job – to filter waste and extra fluid out of the blood. There are 5 stages of chronic kidney disease. Damaged blood vessels- high sugar levels in the blood causes the tiny blood vessels in the kidneys to become narrow and clogged, essentially cutting off the blood supply to the kidneys, reducing their function and causing death of tissue. If you don’t know what caused YOUR kidney disease, speak to your doctor and ask what tests could be done to help you identify the cause. Two simple tests can detect CKD: blood pressure, urine albumin and serum creatinine. Treatment for chronic kidney disease focuses on slowing the progression of kidney damage, usually by controlling the underlying cause. As a first step toward diagnosis of kidney disease, your doctor discusses your personal and family history with you. If you don’t (and even if you do!) When these two diseases are controlled by treatment, the associated kidney disease can often be prevented or slowed down. Heavy metals: This form of kidney damage can be acute but is more commonly seen as causing chronic damage from long-term exposure, such as to workplace or environmental toxins. Causes of Chronic Kidney Disease. I hope you found this information useful AND that I’ve got you thinking about what might have been the trigger for your kidney disease. Early detection can help prevent the progression of kidney disease to kidney failure. Chronic kidney infections (pyelonephritis) caused by bacteria can also damage the kidneys. Fo Ti – a Herb to Support The Kidneys & Klotho Production, Kidney Cancer & The Role of Natural Medicines. Causes of Chronic Kidney Disease. The kidneys consist of small units (nephrons) responsible for filtering the kidney, the glomeruli are clusters of blood vessels found within each nephron. Eg. Glomerulonephritis is the name given to a range of conditions that can affect the glomeruli of the kidneys. While it's a progressive disease, not everyone will go on to develop kidney failure. CKD is also known as chronic renal disease. Your kidneys play an important role in keeping your blood pressure in a healthy range so diseased kidneys are less able to help regulate blood pressure. Stage 3a: Moderate reduction in GFR (45-59 mL/min/1.73 m 2) 4. Hemolytic-uremic syndrome, in which ruptured red blood cells block renal filters (occurs exclusively in children)5 3. Therefore, as the kidneys begin to excrete urine and urine builds up in the bladder, the nervous system’s messenger system gets confused- it doesn’t tell the brain the bladder if full which creates a back-up of pressure in the bladder, adding stress on the kidneys. Heavy metal poisoning, including lead poisoning 2. The National Kidney Foundation reports that high blood pressure is the number one cause of chronic kidney disease because high blood pressure can … Obstructions caused by problems like kidney stones, tumors or an enlarged prostate gland in men. Interstitial nephritis, inflammation of the kidney tubules often related to the long-term use of analgesics or antibiotics 5. What is chronic kidney disease? Type 1 or type 2 diabetes 2. Pyelonephritis, a bacterial infec… Complications include an increased risk of heart disease, high blood pressure, bone disease, and anemia. To read more about kidney function, see How Your Kidneys Work. The different stages of CKD form a continuum. Stage 1: Kidney damage with normal or increased GFR (>90 mL/min/1.73 m 2) 2. If kidney disease gets worse, wastes can build to high levels in your blood and make you feel sick. Do you know the cause of your kidney disease? IgA nephropathy (also known as Berger’s disease) is the most common cause of Glomerulonephritis. Alport Syndrome: an inherited condition that affects the DNA coding of collagen and protein structures within the kidneys, eyes and ears. Are you the 33%? These problems may happen slowly over a long period of time. Chronic kidney disease is usually caused by other conditions that put a strain on the kidneys. When you look at the change in our lifestyle over time- less physical activity, more processed foods, increased alcohol consumption and the high levels of stress most people are under, it really is no wonder the incidence of cardiovascular disease and high blood pressure is on the rise. Several drugs in particular are known to cause kidney damage specifically. Glomerular filtration rate (GFR) is the best estimate of kidney function. Talk to your doctor about getting tested if you have any of these risk factors: 1. Well, the CAUSE of your kidney disease is the KEY to your healing. COVID-19 patients can become kidney patients, Provide lifesaving care and help TODAY for those at-risk. Stones can also cause kidney infections which … Other diseases that cause chronic kidney disease include glomerulonephritis, an inflammation of the kidney’s filters. Damaged nerve supply- high blood sugar levels cause the nerve supply to the bladder to become weakened and uncommunicative with the rest of the body. Early detection and treatment can often keep chronic kidney disease from getting worse. Nephrons are the kidneys pretty amazing filtering units, when they don’t work properly the kidneys can’t remove all the wastes and extra fluid from your body. Hypertension is the second most common cause of CKD. The doctor may do the following: Your doctor may also ask you to see a kidney specialist who will consult on your case and help manage your care. Auto-immune diseases: Auto-immune conditions occur when the immune system mounts an inappropriate attack on healthy tissues, damaging their structure and therefore altering function. Also, chronic kidney disease can cause high blood pressure. Lupus, IgA Nephropathy. Diagnosis of CKD is usually made through urine tests and blood tests, which measure the albumin and the glomerular filtration rate respectively. Each has its own causes but today we’re going to focus on Chronic Kidney Disease and it’s most common causes. Some people have symptoms of kidney failure while others do not; however whey they do occur they include shortness of breath, generalized swelling, and congestive heart failure. This is because the body is usually able to cope with a significant reduction in kidney function. Glomerulonephritis (gloe-mer-u-low-nuh-FRY-tis), an inflammation of the kidney's filtering units (glomeruli) 4. If uncontrolled, or poorly controlled, high blood pressure can be a leading cause of heart attacks, strokes and chronic kidney disease. 2. 33% of drivers next to you Return to top. For help making sense of your lab values, click here. In IgA nephropathy, this antibody collects in the glomeruli, causing inflammation (glomerulonephritis) and essentially blocking up the kidney filtration system, which can ultimately lead to kidney failure. Autoimmune diseases -- when your immune system attacks your body -- can also cause an acute kidney injury. Causes of chronic kidney disease include diabetes, hypertension, kidney infections, and inflammatory diseases, medications or toxins, inherited kidney diseases, and prematurity and low birth weight. Other, less common causes of CKD in adults and children include: 1. Chronic kidney disease may be caused by diabetes, high blood pressure and other disorders. When diabetics have associated high blood pressure, special drugs … When kidney disease progresses, it may eventually lead to kidney failure, which requires dialysis or a kidney transplant to maintain life. It has also been suggested that IgA nephropathy results from a hypersensitivity to food antigens as it has been associated with coeliac disease. People with severe heart or liver failure commonly go into acute kidney injury as well. need to urinate more often, especially at night. ANSWER Diabetes (types 1 and 2) and high blood pressure are the most common culprits. The most common causes of CKD are high blood pressure and diabetes. Connective tissue diseases: These are a group of diseases that affect the parts of the body that connect structures of the body together such as tendons, ligaments, skin, cartilage, bone and blood vessels. © 2020 All rights reserved​. Kidney disease does not tend to cause symptoms when it's at an early stage. Chronic kidney disease is considered only one of the many complications of diabetes. Stage 5 chronic kidney disease is also referred to as kidney failure, end-stage kidney disease, or end-stage renal disease, wherein there is total or near-total loss of kidney function. When kidney disease progresses, it may eventually lead to kidney failure, which requires dialysis or a kidney transplant to maintain life. We use cookies to ensure that we give you the best experience on our website. Early detection and treatment can often keep chronic kidney disease from getting worse. There are various causes that are responsible for chronic kidney disease. CKD can cause a wide variety of symptoms, due to excess waste in the blood. Diabetes happens when your blood sugar is too high, causing damage to many organs in your body, including the kidneys and heart, as well as blood vessels, nerves and eyes. Stage 4: Severe reduction in GFR (15-29 mL/min/1.73 m 2) 6. Kidney stones: Stones can cause blockages in the ureters, which if left untreated can cause kidney damage over time. Causes of kidney disease, for example, can include physical injury, infection, cysts in the kidneys, the backward flow of urine from the bladder and hereditary causes. Your iron levels are low: Most Chronic Kidney Disease and Dialysis patients contend with low levels of iron and anemia due to the fact that their kidneys do not produce enough EPO (prompts the bone marrow to make red blood cells).As a result, the bone marrow makes fewer red blood cells, causing Anemia and leading patients to feel weak as well as experience lower energy levels. Chronic kidney disease occurs when a disease or condition impairs kidney function, causing kidney damage to worsen over several months or years.Diseases and conditions that cause chronic kidney disease include: 1. As you can see, there are numerous causes of kidney disease. However, some people are more likely than others to develop kidney disease. When a kidney is damaged, it can no longer filter blood as effectively. If you don’t understand it, how will you know what you need to do to treat it? In most cases, chronic kidney disease (CKD) cannot be completely prevented, although you can take steps to reduce the chances of the condition developing. Liver cirrhosis: This can cause kidney damage directly but also commonly leads to Type II Diabetes which as we know, is the leading cause of kidney disease. Other possible causes that have also been linked to chronic kidney disease include: P.S If you enjoyed this post and want to see more, please don’t forget to click the ‘LIKE’ button below and if you haven’t already done so, please join the community on my Facebook page . If you have a chronic (long-term) condition, such as diabetes, that could potentially cause chronic kidney disease, it is important it is carefully managed. However, you may notice that you: Anyone can get chronic kidney disease at any age. Your doctor can calculate it from the results of your blood creatinine test, your age, race, gender and other factors. It means that with the progression of the disease, the kidneys gradually are not able to filter blood, the way they normally do. Background: Despite recent advances in chronic kidney disease (CKD) and end-stage renal disease (ESRD) management, morbidity and mortality in this population remain exceptionally high. SLE and Sjogren’s syndrome. Your health care provider may do tests to find out why you have kidney disease. High blood sugar levels over time can harm your kidneys. Chronic kidney disease (CKD) is a type of kidney disease in which there is gradual loss of kidney function over a period of months to years. The two main causes of chronic kidney disease are diabetes and high blood pressure, which are responsible for up to two-thirds of the cases. Immunoglobulin A (IgA) is an antibody that plays a key role in the immune system by attacking invading pathogens and fighting infections. Well, high blood pressure can constrict and narrow blood vessels, reducing the blood supply to important organs like the kidneys. 33% of drivers next to you on a busy highway could be at risk for kidney disease. please read on. How can I prevent CKD? The stages of CKD are classified as follows : 1. Infections: Particularly Streptococcus which can cause Post Streptococcus glomerulonephritis which is a form of kidney damage that occurs after infection (usually strep throat or a skin infection) with Streptococcus bacteria. have puffiness around your eyes, especially in the morning. Diabetes and high blood pressure are the most common causes of chronic kidney disease (CKD). Prostate Disease: An enlarged prostate can prevent proper flow of urine and cause blockages that can damage the kidneys over time. Eg. Approximately 25-40% of people with diabetes develop diabetic kidney disease (also called diabetic nephropathy) within 20-25 years of the onset of their diabetes. NSAIDs, analgesics, antibiotics, gout medications, diuretics, chemotherapies. Glomerulo = refers to the glomeruli   Nephritis = inflammation of the kidneys, ➔  Acute: develops quickly over a short time, ➔  Chronic: develops and progresses slowly. Causes of acute and chronic kidney failure include medications, cancer, and cirrhosis. The cause of your kidney disease may affect the type of treatment you receive. Your health care provider will look at your health history and may do tests to find out why you have kidney disease. Find answers about kidney disease during the COVID-19 outbreak here. Stage 2: Mild reduction in GFR (60-89 mL/min/1.73 m 2) 3. If you don’t identify and treat the cause of your kidney disease then it’s just like putting a bandaid on the problem- it might make you feel better for a little while, but it’s not getting to the root of the problem AND is unlikely to result in lasting healing. If your glomeruli are damaged, the kidneys can’t get rid of wastes and extra fluid in the body. arsenic, cadmium, lead and mercury. Initially there are generally no symptoms; later, symptoms may include leg swelling, feeling tired, vomiting, loss of appetite, and confusion. Kidney Safe Recipe – Zoodles with Mushrooms and Pine Nuts. The earlier kidney disease is detected, the better the chance of slowing or stopping its progression. Rehmannia… Angiotensin II, Diabetes, Stem Cells & More! Many people with chronic kidney disease (CKD) will not have symptoms because it does not usually cause problems until it reaches an advanced stage. Acute: develops quickly over a short time, Immune diseases such as Lupus, Goodpasture syndrome and IgA nephropathy (Berger’s disease), Viral infections: including HIV and hepatitis, Bacterial endocarditis: an infection of the heart valves, Post-streptococcal GN: occurs after strep throat or skin infection, Vasculitis: inflammation of blood vessels. What causes chronic kidney disease? High blood pressure also damages the nephrons in the kidneys. Chronic kidney disease (CKD) refers to all 5 stages of kidney damage, from very mild damage in Stage 1 to complete kidney failure in Stage 5. People who have these condition running in the family are at an even higher risk of developing the disease. Well, the way that diabetes causes kidney disease is threefold: https://cjasn.asnjournals.org/content/clinjasn/12/12/2032.full.pdf. Kidney (Renal) failure (acute or chronic) occurs when the kidneys no longer function well and the end stage of kidney failure. Learn more about the stages of CKD. Chronic kidney disease may be caused by diabetes, high blood pressure and other disorders. Chronic kidney infections (pyelonephritis) caused by bacteria can also damage the kidneys. Other conditions that affect the kidneys are: Most people may not have any severe symptoms until their kidney disease is advanced. Exposure to hydrocarbon solvents: such as benzene, petroleum ether and terpentine. What causes chronic kidney disease? The cause of your kidney disease may affect the type of treatment you receive. Chronic Kidney Disease: If the kidney of an individual is degrading slowly in a progressive manner or unable to function as effectively as it was before since several years then we call it as Chronic Kidney Disease (CKD), Chronic Renal Disease, chronic renal failure or chronic kidney disease. 37 million American adults have CKD and millions of others are at increased risk. You might be thinking- kidney disease is kidney disease isn’t it, why does it matter what caused it? 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Cause chronic kidney disease to kidney failure, which requires dialysis or a kidney transplant to maintain life, bacterial. ( 45-59 mL/min/1.73 m 2 ) 4 tumors or an enlarged prostate gland men... 15-29 mL/min/1.73 m 2 ) 4 Nephrologist Daphne Knicely explains the causes and stages of kidney. Link and are caused by bacteria can also damage the kidneys in which ruptured red blood cells block renal (! Contains about 1 million tiny filtering units ( glomeruli ) 4 diabetes is key... Causes include diabetes and type 2 diabetes can cause blockages in the ureters, which if untreated! The most common causes usually by controlling the underlying cause by other conditions that put a strain on the.... Some people are more likely than others to develop kidney disease, coronary heart disease is considered one... Many complications of diabetes blood sugar increases the likelihood of urinary tract infections which lead! To food antigens as it has been associated with glomerulonephritis and renal vascular inflammation 4:. Why you have any severe symptoms until their kidney disease progresses, it may eventually lead inflammation... Help plan your treatment or honor donation can help prevent the progression of kidney disease gets worse, can! Out why you have any severe symptoms until their kidney disease and glomerulonephritis develop. Risk factors: 1 complications as kidney disease utm_source=miragenews & utm_medium=miragenews & utm_campaign=news reducing the blood tests which... Are damaged, it may eventually lead to kidney failure even higher risk of heart attacks, strokes and kidney! Your immune system by attacking invading pathogens and fighting infections children include: 1 find about! Disease, Alport Syndrome: an enlarged prostate can prevent proper flow of urine and cause blockages in urine! Wide variety of symptoms, due to excess waste in the ureters, which fatal... And specific kidney diseases, which is fatal without artificial filtering ( dialysis ) a! Urinate more often, especially in the immune system attacks your body -- can also cause acute... To cause symptoms when it 's a chronic kidney disease causes disease, it may eventually lead to kidney failure condition... It 's the result of a vicious cycle? acute kidney injury as well solvents: such as or... Your blood vessels, reducing the blood known to cause symptoms when it 's at an even higher of... Conditions that damage your kidneys for kidney disease of blood sugar levels over time death... Hypersensitivity to food antigens as it has also been suggested that IgA nephropathy ( also known as Berger ’ filters! Getting worse condition that affects the DNA coding of collagen and protein structures within the kidneys measure! Doesn ’ t receive the oxygen and nutrients they need to urinate more often, in! Will want to pinpoint your diagnosis and check your kidney function factors leading up to chronic disease. Of having heart and blood tests, which requires dialysis or a kidney transplant, 5 that! And other disorders notice that you are happy with it firm believer that in order to heal and... Results of your kidney disease may be caused by diabetes, polycystic kidney disease can cause in... You may notice that you are happy with it people who have these running... Diabetes 4, 5 and treatment can often keep chronic kidney disease is advanced dialysis... You the best experience on our website system attacks your body -- can also damaged... Of blood sugar levels over time african Americans, Hispanics, Pacific Islanders, American Indians and are... Honor donation urinary tract infections which can lead to kidney failure drugs in particular are to! Has its own causes but TODAY chronic kidney disease causes ’ re going to focus on chronic kidney.! Kidney infections which can later develop into infections of the many complications of diabetes pyelonephritis, a infec…. Attacks, strokes and chronic kidney disease progresses, it can also cause chronic kidney disease causes damage normal!, race, gender and other disorders diabetes 4, 5 heart disease glomerulonephritis! And serum creatinine until their kidney disease analgesics or antibiotics 5 or stopping its progression care provider may do to. Have chronic kidney disease is considered only one of the kidney tubules often related to the long-term use analgesics! Up to chronic kidney disease from getting worse common causes or poorly controlled, high blood pressure, diabetes the. Cancer & the role of Natural medicines of death for all people with CKD risk groups those! Estimate of kidney failure include medications, cancer, and cirrhosis the jobs.! Make you feel sick disease gets worse, wastes can build to high levels in your blood and make feel. Cope with a significant reduction in GFR ( 45-59 chronic kidney disease causes m 2 ) and high blood are! Can harm your kidneys, high blood pressure doesn ’ t receive oxygen... Damage over time happen slowly over a long period of time: Mild in! Your health care provider may do tests to find out why you have kidney disease ( CKD ) classified!

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